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Uruguay Sodium p-aminosalicylate
Category:
UruguaySodium p-aminosalicylate
Product Description
Sodium aminosalicylate: English name: SodiumAmimosalicylate. Due to Mycobacterium tuberculosis caused by pulmonary and extrapulmonary tuberculosis disease has a very good therapeutic effect This product is white or white crystalline or crystalline powder, odorless, sweet and salty. Soluble in water, slightly soluble in ethanol, insoluble in ether.
It is suitable for pulmonary and extrapulmonary tuberculosis caused by Mycobacterium tuberculosis, and inhibits the synthesis of p-aminobenzoic acid of Mycobacterium tuberculosis, which can inhibit its growth. It has a bacteriostatic effect only on Mycobacterium tuberculosis. The oral absorption was good with a Vd of 0.23L/kg. About 50% of the drug acetylation in the body, 80% of the drug (including metabolites) excreted by the urine, renal dysfunction should be noted. Good absorption from the gastrointestinal tract. It is absorbed more rapidly than other salicylates.
| Product Name | Sodium p-aminosalicylate; 4-amino -2-hydroxybenzoic acid sodium salt |
| English Name | Sodium 4-aminosalicylate dihydrate |
| Alias | 4-AminosAlibabacylic acid sodium salt dihydrate; 4-Amino-2-hydroxybenzoic acid sodium salt dihydrate |
| molecular structure formula | ![]() |
| Molecular formula | C7H6NNaO3.2(H2O) |
| molecular weight | 211.15 |
| CAS Login Number | 6018-19-5 |
| EINECS login number | |
| SMILES | 01(+++1)N)O |
| InChI | 1S/C7H7NO3.Na.2H2O/c8-4-1-2-5(7(10)11)6(9)3-4;;;/h1-3,9H,8H2,(H, 10.11);;2*1H2/q; 1;; |
| InChIKey | MONTHS |
| Melting Point | 250-254 °C |
| water soluble | Dissolved |
| Use | It is suitable for pulmonary and extrapulmonary tuberculosis caused by Mycobacterium tuberculosis, and inhibits the synthesis of p-aminobenzoic acid of Mycobacterium tuberculosis, which can inhibit its growth. It has a bacteriostatic effect only on Mycobacterium tuberculosis. The oral absorption was good with a Vd of 0.23L/kg. About 50% of the drug acetylation in the body, 80% of the drug (including metabolites) excreted by the urine, renal dysfunction should be noted. Good absorption from the gastrointestinal tract. It is absorbed more rapidly than other salicylates. |
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